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automated time lapse microscopy  (BioSense Solutions ApS)


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    Structured Review

    BioSense Solutions ApS automated time lapse microscopy
    Summary of results from time-lapse <t> microscopy </t> experiments (6 and 24 h) and spot assay (24 h) for double-carbapenem combinations against clinical carbapenemase-producing E. coli . MIC values for ertapenem, meropenem, and doripenem are classified according to EUCAST clinical breakpoints, version 12.0. Amino acid changes in β-lactamases are written in parentheses. Detected loss of function mutations in porin-encoding genes (OmpC/F) are presented. Carbapenem combinations showing an enhanced effect in the time-lapse <t> microscopy </t> experiments or synergy in the spot assay are highlighted in orange. Synergistic combinations that also showed a bactericidal effect are marked with a thick outline.
    Automated Time Lapse Microscopy, supplied by BioSense Solutions ApS, used in various techniques. Bioz Stars score: 95/100, based on 57 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/automated+time+lapse+microscopy/pmc09686504-269-0-4?v=BioSense+Solutions+ApS
    Average 95 stars, based on 57 article reviews
    automated time lapse microscopy - by Bioz Stars, 2026-08
    95/100 stars

    Images

    1) Product Images from "Evaluation of In Vitro Activity of Double-Carbapenem Combinations against KPC-2-, OXA-48- and NDM-Producing Escherichia coli and Klebsiella pneumoniae"

    Article Title: Evaluation of In Vitro Activity of Double-Carbapenem Combinations against KPC-2-, OXA-48- and NDM-Producing Escherichia coli and Klebsiella pneumoniae

    Journal: Antibiotics

    doi: 10.3390/antibiotics11111646

    Summary of results from time-lapse  microscopy  experiments (6 and 24 h) and spot assay (24 h) for double-carbapenem combinations against clinical carbapenemase-producing E. coli . MIC values for ertapenem, meropenem, and doripenem are classified according to EUCAST clinical breakpoints, version 12.0. Amino acid changes in β-lactamases are written in parentheses. Detected loss of function mutations in porin-encoding genes (OmpC/F) are presented. Carbapenem combinations showing an enhanced effect in the time-lapse  microscopy  experiments or synergy in the spot assay are highlighted in orange. Synergistic combinations that also showed a bactericidal effect are marked with a thick outline.
    Figure Legend Snippet: Summary of results from time-lapse microscopy experiments (6 and 24 h) and spot assay (24 h) for double-carbapenem combinations against clinical carbapenemase-producing E. coli . MIC values for ertapenem, meropenem, and doripenem are classified according to EUCAST clinical breakpoints, version 12.0. Amino acid changes in β-lactamases are written in parentheses. Detected loss of function mutations in porin-encoding genes (OmpC/F) are presented. Carbapenem combinations showing an enhanced effect in the time-lapse microscopy experiments or synergy in the spot assay are highlighted in orange. Synergistic combinations that also showed a bactericidal effect are marked with a thick outline.

    Techniques Used: Time-lapse Microscopy, Spot Test

    Summary of results from time-lapse  microscopy  experiments (6 and 24 h) and spot assay (24 h) for double-carbapenem combinations against clinical carbapenemase-producing K. pneumoniae . MIC values for ertapenem, meropenem, and doripenem are classified according to EUCAST clinical breakpoints, version 12.0. Amino acid changes in β-lactamases are written in parentheses. Detected loss of function mutations in porin-encoding genes (OmpK36/35) are presented. Carbapenem combinations showing an enhanced effect in the time-lapse  microscopy  experiments or synergy in the spot assay are highlighted in orange. Synergistic combinations that also showed a bactericidal effect are marked with a thick outline.
    Figure Legend Snippet: Summary of results from time-lapse microscopy experiments (6 and 24 h) and spot assay (24 h) for double-carbapenem combinations against clinical carbapenemase-producing K. pneumoniae . MIC values for ertapenem, meropenem, and doripenem are classified according to EUCAST clinical breakpoints, version 12.0. Amino acid changes in β-lactamases are written in parentheses. Detected loss of function mutations in porin-encoding genes (OmpK36/35) are presented. Carbapenem combinations showing an enhanced effect in the time-lapse microscopy experiments or synergy in the spot assay are highlighted in orange. Synergistic combinations that also showed a bactericidal effect are marked with a thick outline.

    Techniques Used: Time-lapse Microscopy, Spot Test



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    Summary of results from time-lapse <t> microscopy </t> experiments (6 and 24 h) and spot assay (24 h) for double-carbapenem combinations against clinical carbapenemase-producing E. coli . MIC values for ertapenem, meropenem, and doripenem are classified according to EUCAST clinical breakpoints, version 12.0. Amino acid changes in β-lactamases are written in parentheses. Detected loss of function mutations in porin-encoding genes (OmpC/F) are presented. Carbapenem combinations showing an enhanced effect in the time-lapse <t> microscopy </t> experiments or synergy in the spot assay are highlighted in orange. Synergistic combinations that also showed a bactericidal effect are marked with a thick outline.
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    Image Search Results


    Summary of results from time-lapse  microscopy  experiments (6 and 24 h) and spot assay (24 h) for double-carbapenem combinations against clinical carbapenemase-producing E. coli . MIC values for ertapenem, meropenem, and doripenem are classified according to EUCAST clinical breakpoints, version 12.0. Amino acid changes in β-lactamases are written in parentheses. Detected loss of function mutations in porin-encoding genes (OmpC/F) are presented. Carbapenem combinations showing an enhanced effect in the time-lapse  microscopy  experiments or synergy in the spot assay are highlighted in orange. Synergistic combinations that also showed a bactericidal effect are marked with a thick outline.

    Journal: Antibiotics

    Article Title: Evaluation of In Vitro Activity of Double-Carbapenem Combinations against KPC-2-, OXA-48- and NDM-Producing Escherichia coli and Klebsiella pneumoniae

    doi: 10.3390/antibiotics11111646

    Figure Lengend Snippet: Summary of results from time-lapse microscopy experiments (6 and 24 h) and spot assay (24 h) for double-carbapenem combinations against clinical carbapenemase-producing E. coli . MIC values for ertapenem, meropenem, and doripenem are classified according to EUCAST clinical breakpoints, version 12.0. Amino acid changes in β-lactamases are written in parentheses. Detected loss of function mutations in porin-encoding genes (OmpC/F) are presented. Carbapenem combinations showing an enhanced effect in the time-lapse microscopy experiments or synergy in the spot assay are highlighted in orange. Synergistic combinations that also showed a bactericidal effect are marked with a thick outline.

    Article Snippet: Automated time-lapse microscopy (oCelloScope, BioSense Solutions ApS, Farum, Denmark) was used as previously described [ , , ] to screen the activity of ertapenem, meropenem, and doripenem both alone and in two-drug combinations against 51 KPC-2-, NDM- and OXA-48-producing clinical E. coli and K. pneumoniae isolates.

    Techniques: Time-lapse Microscopy, Spot Test

    Summary of results from time-lapse  microscopy  experiments (6 and 24 h) and spot assay (24 h) for double-carbapenem combinations against clinical carbapenemase-producing K. pneumoniae . MIC values for ertapenem, meropenem, and doripenem are classified according to EUCAST clinical breakpoints, version 12.0. Amino acid changes in β-lactamases are written in parentheses. Detected loss of function mutations in porin-encoding genes (OmpK36/35) are presented. Carbapenem combinations showing an enhanced effect in the time-lapse  microscopy  experiments or synergy in the spot assay are highlighted in orange. Synergistic combinations that also showed a bactericidal effect are marked with a thick outline.

    Journal: Antibiotics

    Article Title: Evaluation of In Vitro Activity of Double-Carbapenem Combinations against KPC-2-, OXA-48- and NDM-Producing Escherichia coli and Klebsiella pneumoniae

    doi: 10.3390/antibiotics11111646

    Figure Lengend Snippet: Summary of results from time-lapse microscopy experiments (6 and 24 h) and spot assay (24 h) for double-carbapenem combinations against clinical carbapenemase-producing K. pneumoniae . MIC values for ertapenem, meropenem, and doripenem are classified according to EUCAST clinical breakpoints, version 12.0. Amino acid changes in β-lactamases are written in parentheses. Detected loss of function mutations in porin-encoding genes (OmpK36/35) are presented. Carbapenem combinations showing an enhanced effect in the time-lapse microscopy experiments or synergy in the spot assay are highlighted in orange. Synergistic combinations that also showed a bactericidal effect are marked with a thick outline.

    Article Snippet: Automated time-lapse microscopy (oCelloScope, BioSense Solutions ApS, Farum, Denmark) was used as previously described [ , , ] to screen the activity of ertapenem, meropenem, and doripenem both alone and in two-drug combinations against 51 KPC-2-, NDM- and OXA-48-producing clinical E. coli and K. pneumoniae isolates.

    Techniques: Time-lapse Microscopy, Spot Test